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The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug effects interactions, allergic reactions, or adverse effects. Patients should also be advised regarding the consumption of alcohol side in combination with. Subjects in the study were taking any marketed angiotensin II receptor blocker, either alone, as a component of a combination product, or as part of a multiple antihypertensive regimen. The primary efficacy and safety study conducted outside the US included 268 patients, with a mean age of 56 years (range 21 to 78 years). In this study, the co-primary endpoints were total ipss and the Erectile Function (EF) domain score of the International Index of Erectile Function (iief). Other side effects and drug interactions are possible, so it is important to discuss any other medications you currently take prior to initiation of treatment with. 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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Tadalafil is excreted side predominantly as metabolites, mainly in the feces (approximately 61 of the dose) and to a lesser extent in the urine (approximately 36 side of the dose). Geriatric Healthy male elderly subjects (65 years or over) had a lower oral clearance of tadalafil, resulting in 25 higher exposure (AUC) with no effect on Cmax relative to that observed in healthy subjects 19 to 45 years of age. Cialis 5 mg for once daily use resulted in statistically significant improvements in the total ipss and in the EF domain of the iief questionnaire. Most of these people already had certain eye problems or risk factors for blood vessel disorders (heart disease, diabetes, high blood pressure, high cholesterol, coronary artery disease, smoking, or being over 50 years old). 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